CBD (Cannabidiol) oil is derived from hemp. Many people confuse hemp with dope, but hemp is a very different CBD OIL Cape Town plant. Dope and hemp may share the same scientific name, Cannabis sativa, but they are not the same.
Dope is cultivated primarily for its psychoactive cannabinoid, a chemical compound called tetrahydrocannabinol or THC, for recreational and healing use. Dope contains both THC and CBD.
Hemp contains very search for of THC, less than 0. 3% compared to marijuana’s hefty 5-35%. The main cannabinoid in hemp is CBD, but there are over 100 other cannabinoids in hemp, as well as compounds that produce tastes and scents called terpenes (e. h. citrusy smell of oranges, unique smell of pine bushes, or sweet flower smell of lavender).
For thousands of years, hemp has been cultivated for food, clothing, fiber, and fuel. It is one of the world’s most ancient domesticated crops. In the early days, hemp was a vital plant in the You. S. During the 1700s, colonial farmers grew hemp mainly for its strong fiber.
However, hemp production stumbled on a screeching halt when the Dope Tax Act of 1937 was passed. Mainstream attitudes towards cannabis begun to sway greatly towards the negative. Hemp became the “evil weed” because it shares the same species as dope although it does not contain marijuana’s abundant THC.
Over the years, many have speculated that the real reason for the anti-cannabis campaign boiled down to the worry that hemp could become a low-cost substitute for paper pulp. American industrialist William Randolph Hearst and the DuPont family had major investments in the bushes and newspaper industries. They initiated a smear campaign to destroy the lucrative hemp market for fear that the rise of hemp would undercut their profits. Nevertheless, years later, it became known that hemp does not contain a high enough concentration of cellulose to be an effective paper substitute.
70 long years later, hemp finally regained its legal status in the You. S. after the passage of the 2018 Farm Bill. Hemp, thought as cannabis with less than 0. 3% THC, is stripped away from Schedule I controlled substances. Hemp-derived products are legal as long as they come from licensed hemp stating. More and more universities and hostipal wards have begun to study it. Americans can now use CBD legally. It can be ordered online and shipped to all or any 50 states.
Dope laws are also changing at a rapid pace across America. Although it is still illegal on the federal level, many states have legalized dope. For the remaining states, some have allowed it for medical use and some recreational use.
The Human Endocannabinoid System (ECS)
Cannabinoids that is generated by our own bodies are called endocannabinoids (the prefix “endo” means within). In the 1990s, researchers made an astonishing discovery that the ECS plays a major role in our overall health.
The ECS maintains constant communication with every organ system within the body.
This communication involves messenger compounds called endocannabinoids and cannabinoid receptors on every cell that accepts them. Think of it as a “key and lock” system. The receptors are locks and the endocannabinoids are keys that bind to these receptors and discover them.
There are two main types of receptors within the ECS – cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2).
Researchers found more than 1, 000 receptors within the body. CB1 receptors are generally largely on lack of feeling cells in the brain and back, as well as the eye and retina. CB2 receptors are mostly found in the immune system and in the bodily organs and flesh, such as brain, spleen, blood cells, gastrointestinal, and urinary tracts.
The body produces two types of endocannabinoids – anandamide and 2-AG. These are transported into the cells through the CB1 and CB2 receptors. Even as age, the body becomes less efficient in producing anandamide and 2-AG. The proper functioning of the ECS also depends on the adequacy of omega-3 in the diet.
Many people have seen the feel good sensation or “high” after strenuous exercise. The elevated mood comes from the release of endorphins. Researchers now know that it is also from an increase in anandamide, which targets mainly the CB1 receptors and, to a lesser extent, the CB2 receptors.
The other endocannabinoid, 2-AG, posts signals across the brain cells and activates both CB1 and CB2 receptors. 2-AG supports brain health, immune health, as well as insulin level of responsiveness.
Researchers have now discovered that both endocannabinoids, anandamide and 2-AG, have a considerable relation to a variety of functions including appetite, energy and balance, immunity, memory, metabolism, nervous system, sleep, and stress response.
Evidence For CBD Health benefits
The Cannabis plant contains over 100 cannabinoids. These compounds closely resemble the human endocannaboids. The main cannabinoid in hemp is CBD, and in dope, THC.
Unlike THC, CBD does not bind inside our cannabinoid receptors. Nevertheless, it does stimulate the activity of both CB1 and CB2 receptors without directly experiencing them. A report by the National Institute of Health found that CBD causes the body to produce more endocannabinoids, especially 2-AG. Moreover, CBD inhibits the degradation of anandamide.
Scientists are now beginning to discover many of CBD’s health benefits:
CBD has been touted for a wide variety of health interests, but the most potent scientific evidence is for its effectiveness in treating two rare drug-resistant childhood epilepsy conditions, particularly Lennox-Gastaut malady (LGS) and Dravet malady (DS). The FDA has recently approved the first ever CBD-derived drug Epidiolex for these conditions. In various studies, CBD was able to reduce the number of seizures, and in some cases it was able to stop them altogether.
CBD may offer an option for treating different types of chronic pain: fibromyalgia, gout, HIV, multiple sclerosis, neuropathic, and rheumatoid arthritis. Studies found that applying CBD oil directly on the problem area helps to lower pain and inflammation. CBD functions by impacting on cannabinoid receptor activity within the body, reducing inflammation, and interacting with neurotransmitters.
Researchers also found that subjects did not build up a tolerance to the effects of CBD, so there was no need to increase dosage continually. Unlike some pain medications, CBD is not habit forming and does not have any intoxicating effects, offering much relief for individuals that have chronic pain.
An oral product called Sativex, which is a combination of CBD and THC, has been approved in a number of countries in Europe and Canada (but not in the You. S. ) to treat pain and muscle fits related to multiple sclerosis.
Another controlled study found that Sativex significantly improved pain during movement, pain at rest, and sleep quality in people with rheumatoid arthritis.
Anxiety and Depression
Clinical assessments have revealed that both dope and CBD may be effective in reducing different forms of anxiety including generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (PTSD).
Not only did participants in the studies felt better, they also reported reduced cognitive disadvantages and anxiousness. Scientists suggest that in addition to impacting on the endocannabinoid system, CBD may influence receptors involved in the modulation of serotonin, a chemical messenger that plays a role in anxiety regulation.
In addition, some studies showed that CBD eases depression and supports psychotic disorders like schizophrenia. (Please note that dope does not help with either and may actually get worse psychosis. )
Researchers found that cancer patients treated with CBD and THC, the psychoactive compound from dope, experienced significant lowering pain. In addition, a one-to-one combination of CBD and THC administered via mouth product reduced side effects associated with cancer treatments like nausea, vomiting, and loss of appetite.
At present, more research needs to be done on whether CBD alone can produce the same beneficial outcomes.
A number of cell culture studies found that cannabinoids can help slow tumor growth, reduce tumor attack, and induce tumor cell death in several types of cancer, including brain, blood, breast, colon, pancreatic, and prostate.
Scientists believe that CBD probably functions by famished cancer cells of energy, making them more sensitive to the bodies immune response, and by blocking a freshly discovered cannabinoid-related cancer walkway. However, human assessments are needed before further results can be drawn.